Barely Significant
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Dr1 (NC2) is present at tRNA genes and represses their transcription in human cells.

Nucleic Acids Res · 2010 · PMC2831321 · PMID 19965767

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The sentences

highly significantP < 0.0001actually significant
Quantitation of binding by qPCR confirms that it is highly significant ( P < 0.0001; Supplementary Figure S8 ).

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Three different siRNAs targeting three different exons of DRAP1 were analysed, but although DRAP1 protein levels were reduced by about 75%, only marginal changes in pre-tRNA and other pol III transcript levels were obtained, that were not consistent and did not reach statistical significance ( Figure 5 and Supplementary Figures S6 and S7 ).

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