In this case the p-value for association, P = 1.9×10 −8 meets conventional levels for genome-wide significance – for example, it is nominally significant at the 0.05 level after a Bonferroni correction for 2.5 million tests, and exceeds the 5×10 −7 threshold used by WTCCC in reporting “strongly associated” variants [26] .
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Genome-wide association of lipid-lowering response to statins in combined study populations.
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