A trend for a positive correlation between plasma SIV RNA and the total frequency of circulating invariant NKT lymphocytes did not reach statistical significance ( Figure 9A ).
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Paucity of CD4+ natural killer T (NKT) lymphocytes in sooty mangabeys is associated with lack of NKT cell depletion after SIV infection.
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However, there was a highly significant positive correlation between the frequency of peripheral blood Vα24 + CD1d TM + and Vα24 + 6B11 + NKT lymphocytes ( Figure 1D ), confirming a dominance of invariant NKT lymphocytes in the CD1d TM + T lymphocyte population.