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The T-allele of TCF7L2 rs7903146 associates with a reduced compensation of insulin secretion for insulin resistance induced by 9 days of bed rest.

Diabetes · 2010 · PMC2844831 · PMID 20107109

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In this study, the slightly elevated rate of hepatic glucose production in carriers of the T-allele ( P = 0.10) at baseline did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.