Cyclin D2 is essential for the compensatory beta-cell hyperplastic response to insulin resistance in rodents.

Diabetes · 2010 · PMC2844846 · PMID 20103709

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did not reach statistical significanceno p-value reported

However, in 25-week-old mice a higher rate of apoptosis was detectable in the D2KO and D2KO/IRS1KO islets, which is consistent with a recent report ( 38 ), although these differences did not reach statistical significance (data not shown).

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