Effect of intensive compared with standard glycemia treatment strategies on mortality by baseline subgroup characteristics: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial.

Moreover, the interaction between self-reported history of neuropathy/nerve problems and glycemia arm continued to remain highly significant ( P = 0.006) after adjusting for age, sex, waist circumference, smoking, diabetes duration, hypoglycemic agents used, history of retinopathy, history of amputation, and systolic blood pressure.

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Here we specifically note those of significance and borderline significance.

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The interactions in the A1C and aspirin use were of marginal significance and can only be considered suggestive and will require additional study.

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