Genetic architecture of plasma adiponectin overlaps with the genetics of metabolic syndrome-related traits.

Diabetes Care · 2010 · PMC2845050 · PMID 20067957

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

borderline significantP = 0.06so close (0.05 < p ≤ 0.1)

BMI and plasma insulin showed a significant ( P < 0.04) shared genetic component with plasma adiponectin of, respectively, −32.4 and −20.0%, whereas our finding for HOMA-IR was borderline significant (genetic correlation [ρ G ] = −18.6%, P = 0.06).

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highly significantno p-value reported

All heritability estimates were highly significant and none of the metabolic syndrome–related traits showed a significant sibship effect estimate (S).

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nominally significantno p-value reported

A nominally significant association was found with plasma insulin and HOMA-IR and ADIPOQ variant rs17300539 after adjustment for plasma adiponectin.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.