LIMD1 is more frequently altered than RB1 in head and neck squamous cell carcinoma: clinical and prognostic implications.

Mol Cancer · 2010 · PMC2848626 · PMID 20226061

Europe PMC DOI

hedged sentences

0.0543

closest p · 1.1× alpha

0.0543

boldest claim

The sentences

borderline significanceP = 0.05427so close (0.05 < p ≤ 0.1)

Comparing the frequency of each allele with that of all other alleles combined, case-control differences were significant for (CA) 20 [ P = 0.000005], (CA) 32 [ P = 0.0082] and borderline significance for (CA) 24 allele [ P = 0.05427].

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a trend towards significanceno p-value reported

Likewise, a trend towards significance of RB1 deletion in advance grade tumors, with nodes of pathology has also been observed [ 31 ].

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showed a trendno p-value reported

Moreover, patients with advanced grade tumor ( P , 0.50; HR, 1.49; CI, 0.46-4.89) having nodal metastasis ( P , 0.42; HR, 1.63; CI, 0.49-5.34) along with RB1 deletion ( P , 0.15; HR, 2.27; CI, 0.74-7.02) showed a trend to have poorer survival, albeit being statistically insignificant.

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