Genetic modifiers of Hb E/beta0 thalassemia identified by a two-stage genome-wide association study.

The FDR is an accepted measure of the significance of multiple association results, while we also state which findings pass the overly conservative Bonferroni threshold to highlight the highly significant findings.

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Tests for genetic association with HbF% within the mild disease group revealed nominally significant results with 14 SNPs in the β-globin gene cluster (Table 3 ).

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