FAM-MDR* assesses marginal significance of the best model by computing the empirical marginal p-value of the pair found.
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FAM-MDR: a flexible family-based multifactor dimensionality reduction technique to detect epistasis using related individuals.
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The sentences
With correction for main effects, PGMDR reports a different near-significant two-locus model involving rs2275703 in CASQ1 and rs1028583 in HNF4A .