In contrast, a study by Steinberg et al, including 4,472 cardiac, orthopaedic and gynaecological patients, showed that the risk of SSI was lowest when antibiotics were administered within the final 30 minutes pre-incision, a difference that did not reach statistical significance [ 16 ].
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The SURgical PAtient Safety System (SURPASS) checklist optimizes timing of antibiotic prophylaxis.
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