highly significantp = 2.71 × 10 −6
This yielded a highly significant association of p = 2.71 × 10 −6 and OR = 3.15 (95% CI: 1.95, 5.09) for the heterozygous genotype under an additive model.
This yielded a highly significant association of p = 2.71 × 10 −6 and OR = 3.15 (95% CI: 1.95, 5.09) for the heterozygous genotype under an additive model.
Four additional SNPs within IKBKAP also showed marginally significant association ( p < 0.03) with HSCR.
Unfortunately, the p value of the replication did not reach statistical significance.