New Genetic Findings in Schizophrenia: Is there Still Room for the Dopamine Hypothesis of Schizophrenia?

Front Behav Neurosci · 2010 · PMC2871716 · PMID 20485477

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nominally significantno p-value reported

Across 118 meta-analyses, a total of 24 genetic variants in 16 different genes ( APOE , COMT , DAO , DRD1 , DRD2 , DRD4 , DTNBP1 , GABRB2 , GRIN2B , HP , IL1B , MTHFR , PLXNA2 , SLC6A4 , TP53 , and TPH1 ) showed nominally significant effects with average summary odds ratios of approximately 1.23.

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