What is the mechanism for persistent coexistence of drug-susceptible and drug-resistant strains of Streptococcus pneumoniae?

J R Soc Interface · 2010 · PMC2871802 · PMID 19940002

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a significant trendno p-value reported

Among these 21 countries, there were only six showing evidence of a trend in the prevalence of penicillin non-susceptibility (decreasing in four, increasing in two), four with a significant trend in the prevalence of penicillin resistance (increasing in two and decreasing in two) and eight with a trend in macrolide resistance (increasing in six and decreasing in two).

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