MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans.

Four carriers of codon 60R had decreased insulinogenic index (β = −83% [−152 to −13], P = 0.02) ( Table 5 ), which remained nominally significant when analyses were adjusted for the difference in BMI (β = −72% [−140 to −5], P = 0.04). 243R was nominally associated with decreased FPG (β = −0.08 mmol/l [−0.16 to −0.01], P = 0.04) ( Table 5 ).

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