Barely Significant
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The effect of tegaserod on symptoms and quality of life in korean women with irritable bowel syndrome with constipation.

J Neurogastroenterol Motil · 2010 · PMC2879829 · PMID 20535328

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a marked trendno p-value reported
In addition, patients with a mixed type of IBS could be enrolled if they showed a marked trend of constipation on the symptom severity questionnaire.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.