Assessing the functional coherence of gene sets with metrics based on the Gene Ontology graph.

Bioinformatics · 2010 · PMC2881388 · PMID 20529941

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a clear trendno p-value reported

The averaged P -values by the count-based metric showed a clear trend as a nearly linear function of the size of the clusters; in contrast, the P -values from the graph-based metric span a broader range, indicating cluster size has little if any impact on its coherence evaluation.

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