Transient reexpression of IRAP in the IRAP-KD adipocytes increased the translocation of GLUT4 to the PM of IRAP-KD adipocytes, an effect that also did not reach statistical significance (p = 0.08).
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Insulin-regulated aminopeptidase is a key regulator of GLUT4 trafficking by controlling the sorting of GLUT4 from endosomes to specialized insulin-regulated vesicles.
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0.0800
0.0800