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Enhanced anti-tumor effects of combined MDR1 RNA interference and human sodium/iodide symporter (NIS) radioiodine gene therapy using an adenoviral system in a colon cancer model.

Cancer Gene Ther · 2010 · PMC2887652 · PMID 20186172

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I-125 uptake in Ad-hNIS-infected cells was slightly higher as compared with uptake for both Ad-hNIS and Ad-shMDR1 infected cells, but did not reach statistical significance.

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