Systematic analysis of cis-elements in unstable mRNAs demonstrates that CUGBP1 is a key regulator of mRNA decay in muscle cells.

PLoS One · 2010 · PMC2888570 · PMID 20574513

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In addition, using this linear model we found that the lengths of 5′UTR and CDS do not significantly influence mRNA decay rates, and the size of 3′UTR is only marginally significant, suggesting specific elements rather than sequence length determine mRNA half life in C2C12 cells.

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