An increasing trend with increasing age at first birth was most pronounced for lobular tumors and unspecified carcinomas; an association in the opposite direction was seen in relation to medullary and tubular tumors.
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Histological type and grade of breast cancer tumors by parity, age at birth, and time since birth: a register-based study in Norway.
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The sentences
Nevertheless, a decreasing trend with age was seen only among nulliparous women when including a missing category in the analysis (results not shown).
On the other hand, the borderline significant association with time since last birth in the age-adjusted analyses suggested an effect of pregnancy-related factors rather than a confounding effect of age.
The estimated decreasing trend with increasing time since birth did not reach statistical significance (Table 4 ).