There were also consequent increases in infectious virion titre in serum in ACP-p21 bearing mice compared to ACP-GFP mice, although the differences did not reach statistical significance - ACP-GFP mean titres 24 and 48 hours pi: 1.74 × 10 5 +/- 1.36 × 10 5 and 2.56 × 10 5 +/- 1.95 × 10 5 pfu/ml (mean +/- s.d. n = 5) respectively.
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p21 Promotes oncolytic adenoviral activity in ovarian cancer and is a potential biomarker.
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