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Senescent mouse cells fail to overtly regulate the HIRA histone chaperone and do not form robust Senescence Associated Heterochromatin Foci.

Cell Div · 2010 · PMC2904742 · PMID 20569479

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A small population, which did not reach statistical significance in these studies, did appear to exhibit nuclear reorganization and chromatin compaction, based on DAPI and macroH2A staining.

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