Impacts of cytosolic phospholipase A2, 15-prostaglandin dehydrogenase, and cyclooxygenase-2 expressions on tumor progression in colorectal cancer.

In the present study, 15-PGDH was found to be expressed in 46.1% (41 of 89) of colorectal cancers, and its expression showed a trend of positive expression in patients with favorable clinicopathologic parameters, such as pT0, well differentiated histologic pattern, normal pre-operative carcinoembryonic antigen levels, and no recurrence ( Table 1 ).

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