Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts.

Crit Care · 2010 · PMC2911747 · PMID 20525286

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did not reach statistical significanceno p-value reported

Patients carrying no mutations or either TLR4 or TIRAP/Mal mutations showed a stronger induction of IL-6 following LPS-stimulation compared with patients with double mutations, although the difference did not reach statistical significance.

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