Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis.

Arthritis Res Ther · 2010 · PMC2911905 · PMID 20534145

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did not reach statistical significanceno p-value reported

An elevated level of aggrecan mRNA was also found at 500 ng/ml of leptin for both BMI patient groups, but the difference with unstimulated cells did not reach statistical significance.

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