Theoretically, a collective inhibition of COMT-mediated O -methylation of endogenous catecholamines (including dopamine and L-DOPA) by these dietary polyphenols could be quite significant in the human body.
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Dual beneficial effects of (-)-epigallocatechin-3-gallate on levodopa methylation and hippocampal neurodegeneration: in vitro and in vivo studies.
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