The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial.

Although there was a marginally significant difference between the groups in the change in CD8+/CD38+ percent from baseline to week 12—there was a median of a 3% decline in the group that added raltegravir versus a 1% increase in the group that added placebo ( p = 0.053 for the comparison, Wilcoxon rank sum test)—the change in CD8+/CD38+ percentage from week 12 to 24 (after the cross-over) did not differ between the treatment groups ( Table 3 ).

also in 26,082 other papers

However, the increased CD4 cell counts during raltegravir intensification in the current study did not reach statistical significance and were not associated with a decrease in T cell activation; therefore, the CD4 cell rise may have been due to chance and should be interpreted cautiously.

also in 111,027 other papers