Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population.

PLoS One · 2010 · PMC2922326 · PMID 20808433

Europe PMC DOI

hedged sentences

0.0150

closest p · 0.3× alpha

0.0700

boldest claim

The sentences

nominally significantP = 0.015actually significant

We found nominally significant associations of 7 SNPs with at least one smoking-related phenotype in the total sample (SI: P = 0.015∼0.023; SQ: P = 0.008∼0.028; SC: P = 0.018∼0.047) and the male sample (SI: P = 0.001∼0.023; SQ: P = 0.001∼0.046; SC: P = 0.01).

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marginally significantP = 0.07so close (0.05 < p ≤ 0.1)

Moreover, the rs16969968 genotype was associated with LC in both former (P<0.0001) and current (P<0.0001) smokers, and a marginally significant trend was observed in never smokers (P = 0.07).

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