In the dentate gyrus, the FKBP51 IRn was significantly decreased in impaired aged mice compared to young mice ( p < 0.05, Dunn’s post hoc test); nonetheless, the difference in the FKBP51 IRn between impaired and unimpaired aged mice did not reach statistical significance ( p > 0.05, Dunn’s post hoc test).
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Short-term recognition memory impairment is associated with decreased expression of FK506 binding protein 51 in the aged mouse brain.
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