Percentage of HGP suppression during the clamp was concordantly higher in PANDER −/− mice but narrowly missed statistical significance (73.4 ± 3.0 vs. 53.3 ± 8.9%, respectively; P = 0.05) ( Fig. 3 B ).
← all excerpts
Targeted disruption of pancreatic-derived factor (PANDER, FAM3B) impairs pancreatic beta-cell function.
2
0.0500
0.0500
The sentences
The hyperinsulinemic-euglycemic clamp studies showed significantly decreased HGP and a strong trend in increased HGP suppression compared with wild-type mice.