Insights into the binding of Phenyltiocarbamide (PTC) agonist to its target human TAS2R38 bitter receptor.

PLoS One · 2010 · PMC2928277 · PMID 20811630

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failed to reach statistical significanceno p-value reported

On the other hand, the maximum activities of M100A and M100V are clearly higher than the activity of WT (although the elevated maximum activity observed for M100V compared to wild-type failed to reach statistical significance because higher concentrations of the agonist could not be applied), showing that this position may affect receptor activation.

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