Role of functional single nucleotide polymorphisms of MMP1, MMP2, and MMP9 in open angle glaucomas.

Remarkably, investigating the association between exfoliation syndrome and XFG and the MMP1 −1607 1G/2G polymorphism, Tsironi and coworkers [ 37 ] reported an allele contrast of borderline significance for exfoliation syndrome (OR=1.47; 95%CI: 1.03–2.10; p=0.04), but not for XFG.

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As for the MMP1 −1607 1G/2G polymorphism, a Greek study showed a trend for association with exfoliation syndrome [ 37 ].

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