Of the individual SNP analyses, only rs6548238 near TMEM18 , rs10838738 in MTCH2 , and rs7498665 near SH2B1 showed nominally significant interactions with physical activity level on BMI or obesity risk ( Tables S3 and S4 ), but none survived adjustment for multiple comparisons.
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Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study.
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