Renal manifestations in scleroderma: evidence for subclinical renal disease as a marker of vasculopathy.

Use of prophylactic ACE inhibitors in SSc does not protect against SRC [ 15 , 43 ], and their use prior to development of SRC may be associated with worse outcomes [ 14 , 44 ] although this data was not adjusted for confounders, and the reported association did not reach statistical significance. 3.9.

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