PDZRN3 negatively regulates BMP-2-induced osteoblast differentiation through inhibition of Wnt signaling.

Mol Biol Cell · 2010 · PMC2938391 · PMID 20668165

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difference was apparentno p-value reported

The BMP-2–induced increase in the abundance of β-catenin in the cytosol was indeed more pronounced in cells expressing PDZRN3 shRNA than in those expressing the scrambled shRNA, and this difference was apparent in both low-serum and growth media ( Figure 7 , B and C).

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