Deficiency of the metalloproteinase-disintegrin ADAM8 is associated with thymic hyper-cellularity.

PLoS One · 2010 · PMC2939894 · PMID 20856819

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In contrast, ADAM8 −/− SP thymocytes showed a trend for lower migration efficiencies towards CCL21 when compared to wt controls ( Figure 7A–D ).

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