Nominally significant correlations were obtained for trails A (ρ=−0.36, p =0.048), indicating that reduced GM volumes across the nine implicated regions were associated with longer times (poorer performance) on this test ( Figure 4 ).
Although trails A was selected for investigation a priori on the basis of its correlation with MRI volumes, it should be noted that the effect on trails A was modest and would only reach marginal significance ( p =0.065) if strict Bonferroni correction were applied against all five domain scores in our neurocognitive battery.