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Association of Tat with promoters of PTEN and PP2A subunits is key to transcriptional activation of apoptotic pathways in HIV-infected CD4+ T cells.

PLoS Pathog · 2010 · PMC2940756 · PMID 20862322

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Inhibition of PPP2R1B did not reach statistical significance in reducing apoptosis in primary CD4+ T-cells, while statistical significance was attained when a siRNA against PTEN was used.

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