Barely Significant
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Pioglitazone and alogliptin combination therapy in type 2 diabetes: a pathophysiologically sound treatment.

Vasc Health Risk Manag · 2010 · PMC2941781 · PMID 20859539

1
hedged sentence
0.0950
closest p · 1.9× alpha
0.0950
boldest claim

The sentences

did not reach statistical significanceP = 0.095so close (0.05 < p ≤ 0.1)
The primary endpoint (composite of death, MI, stroke, leg amputation, acute coronary syndrome, cardiac bypass, or leg revascularization) was reduced by 10% but this did not reach statistical significance because of an increase in leg revascularization (HR 0.90, 95% CI 0.80–1.02; P = 0.095).

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