Patients with the cutaneous limited form of the disease showed no statistical difference in CEC and EPC numbers compared to the patients with the diffuse cutaneous form, even if FACS analysis showed a trend towards an increased number of CECs and EPCs in patients with the diffuse cutaneous form (data not shown).
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Gene expression profiling in circulating endothelial cells from systemic sclerosis patients shows an altered control of apoptosis and angiogenesis that is modified by iloprost infusion.
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