High mobility group box 1 potentiates the pro-inflammatory effects of interleukin-1β in osteoarthritic synoviocytes.

Arthritis Res Ther · 2010 · PMC2945068 · PMID 20799933

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

did not quite reach statistical significanceP < 0.07so close (0.05 < p ≤ 0.1)

As illustrated in Figure 1b , a statistically significant decrease in HMGB1 was found in OA cell nuclei when compared with normal ( P < 0.03), and, although there was more positive staining in the extra-nuclear (cytoplasm and in the cell vicinity) compartment, this did not quite reach statistical significance ( P < 0.07).

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did not reach statistical significanceno p-value reported

HMGB1 treatment in nonstimulated cells resulted in increased transcriptional activity, although it did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.