Analysis and modeling of ensemble recordings from respiratory pre-motor neurons indicate changes in functional network architecture after acute hypoxia.

Those who were synchronized before and/or after hypoxia had a significant trend to decrease their synchrony ( p < 0.05, Wilcoxon sign rank test), as revealed by the histogram of difference in synchrony, which is clearly skewed to the left (Figure 5 B).

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As in the experiments, the number of coincident spikes versus the harmonic mean of the number of spikes in the pair fit a quadratic function whose slope at any point was slightly lower after hypoxia, which indicates an overall trend across the population to decrease synchrony after hypoxia.

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