Barely Significant
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Nitric oxide is negatively correlated to pain during acute inflammation.

Mol Pain · 2010 · PMC2949722 · PMID 20843331

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Local infusion of the NO donor glyceryl trinitrate at the site of surgery, showed a small analgesic effect that did not reach statistical significance in the sample size used.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.