Genetic signatures in the envelope glycoproteins of HIV-1 that associate with broadly neutralizing antibodies.

Position 301 (PNLG) reached borderline significance in the complete scan of Env when testing for an association between the preservation or loss of specific PNLGs and the b12 neutralization (p = 0.019, q = 0.30, OR = 0.23).

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None had a q-value<0.2, and the only one that showed borderline significance was found at position 149 (it is noted in Table 2 ).

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