Treating viral exacerbations of chronic obstructive pulmonary disease: insights from a mouse model of cigarette smoke and H1N1 influenza infection.

Along similar lines, the viral titres observed at both days five and seven post-infection did not reach statistical significance; in contrast, in our model of cigarette smoke exposure and Haemophilus influenzae infection, systemic corticosteroid treatment significantly impaired bacterial clearance from the lungs of infected mice.

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