Infarct size unadjusted for differences in area at risk was also reduced in the ADC-1004 group, although it did not reach statistical significance (ADC-1004: 23.0 ± 3.0 vs control: 27.1 ± 1.4%LVM, p = 0.16) (Figure 2 ).
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Treatment with the C5a receptor antagonist ADC-1004 reduces myocardial infarction in a porcine ischemia-reperfusion model.
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