Changes in deceleration capacity of heart rate and heart rate variability induced by ambient air pollution in individuals with coronary artery disease.

For the 24-hour recordings, the pNN50-effect seen with the EC- and OC-averages of 24-47 hours before the recording showed a trend towards a stronger effect in individuals not taking beta-adrenergic receptor blockers (data not shown).

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In addition, highly significant effects were found for DC which decreased in association with PM 2.5 , EC and OC concurrent with the ECG recordings as well as with a lag of up to 47 hours.

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The sensitivity analyses excluding the two participants on anti-arrhythmic therapy (23 observations for the 5-minute ECGs and 7 observations for the 24-hour ECGs) showed slightly smaller effect estimates with some effects changing from significant to borderline significant.

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