Pulsatile stress in middle-aged patients with type 1 or type 2 diabetes compared with nondiabetic control subjects.

There was a highly significant inverse correlation between pulsatile stress and baroreflex gain in patients with type 2 diabetes ( r = −0.719; P = 0.0001) but not in overweight/obese control subjects ( r = −0.272; NS).

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Careful analysis of the two pulse pressure curves showed different kinetics in pulse pressure increases, with a second phase increase in pulse pressure in patients with type 1 diabetes that was not observed in patients with type 2 diabetes; however, the between-group difference during the second part of squatting did not reach statistical significance ( Fig. 1 C ).

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