While the decrease in renal cyst burden in female rats did not reach statistical significance after 7 weeks of feeding ( P = .06), there was a significant decrease in the pioglitazone-fed females after 14 weeks ( Table 1 ; Figure 1 ).
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Pioglitazone Attenuates Cystic Burden in the PCK Rodent Model of Polycystic Kidney Disease.
1
0.0600
0.0600